Publications

Fiedler, E.; H.-P. Fiedler, A. Gerhard, W. Keller-Schierlein, W.A. König & H. Zähner: Synthese und Biosynthese substituierter Tryptanthrine. Arch. Microbiol. 107: 249-256, 1976.

Fiedler, H.-P.: Isolierung von mikrobiellen Stoffwechselprodukten mit Hilfe von Adsorberharzen. Chem. Rundschau 30: 2-3, 1977.

Publication

Fiedler, H.-P. & J. Sauerbier: Isolation and quantitative determination of siderochromes. Europ. J. Appl. Microbiol. Biotechnol. 5: 51-57, 1978.

Publication

Hartmann, A.; H.-P. Fiedler & V. Braun: Uptake and conversion of the antibiotic albomycin by Escherichia coli K112. Europ. J. Biochem. 99: 517-524, 1979.

Publication

Hagenmaier, H.; W.A. König, H. Zähner, H.-P. Fiedler, W. Dehler, A. Keckeisen, H. Holst & G. Zoebelein: Neue Nikkomycine, ein Verfahren zu ihrer Herstellung, sowie ihre Verwendung als Schädlingsbekämpfungsmittel (1979). Europ. Patentschrift 0022 964 vom 9.2.1983, Anmeldetag: 4.7.1980, Offenlegungstag: 28.1.1981, 1981.

Publication

König, W.A.; W. Hass, W. Dehler, H.-P. Fiedler & H. Zähner: Strukturaufklärung und Partialsynthese des Nucleosidantibiotikums Nikkomycin B. Liebigs Ann. Chem. 1980: 622-628, 1980.

Publication

Hagenmaier, H.; A. Keckeisen, W. Dehler, H.-P. Fiedler, H. Zähner & W.A. König: Konstitutionsaufklärung der Nikkomycine I, J, N und M. Liebigs Ann. Chem. 1981; 1018-1024, 1981.

Publication

Fiedler, H.-P.: Quantitation of nikkomycins in biological fluids by ion-pair reversed-phase high-performance liquid chromatography. J. Chromatogr. 204: 313-318, 1981.

Fiedler, H.-P.: Preparative scale HPLC of ferricrocin, a microbial product. J. Chromatogr. 209: 103-106, 1981.

Publication

Fiedler, H.-P.; W. Wörner, H. Zähner, H.P. Kaiser, A. Müller & W. Keller-Schierlein: Isolation and characterization of niphithricins A, B, and elaiophylin, antibiotics produced by Streptomyces violaceoniger. J. Antibiot. 34: 1107-1118, 1981.

Publication

Fiedler, H.-P.; R. Kurth & W. Dehler: Nikkomycin quantitation in fermentation process by high-performance liquid chromatography. Biotechnol. Lett. 3: 303-308, 1981.

Publication

Fiedler, H.-P.; R. Kurth, J. Langhärig, J. Delzer & H. Zähner: Nikkomycins, microbial inhibitors of the chitin synthase. J. Chem. Technol. Biotechnol. 32: 271-280, 1982.

Publication

Delzer, J.; H.-P. Fiedler, H. Müller, H. Zähner, R. Rathmann, K. Ernst & W.A. König: New nikkomycins by mutasynthesis and directed fermentation. J. Antibiot. 37: 80-82, 1984.

Fiedler, H.-P.: Screening for new microbial products by HPLC using a photodiode array detector. J. Chromatogr. 316: 487-494, 1984.

Publication

Fiedler, H.-P. & H.P. Reuschenbach: Precolumnm switching in HPLC quantitation of small amounts of microbial metabolites as an alternative method to off-line extraction. Chromatographia 19: 246-250, 1985.

Publication

Fiedler, H.-P.; F. Walz, A. Döhle & H. Zähner: Albomycin: studies on fermentation, isolation and quantitative determination. Appl. Microbiol. Biotechnol. 21: 341-347, 1985.

Publication

Fiedler, H.-P.; A. Plaga & R. Schuster: Automated on-column derivatization of the antibiotics phosphinothricin and phosphinothricyl-alanyl-alanine with o-phthalaldehyde and microbore column high-performance liquid chromatography for quantitative determination in biological cultures. J. Chromatogr. 353: 201-206, 1986.

Publication

Fiedler, H.-P.; J. Rohr & A. Zeeck: Elloramycins B, C, D, E and F: minor congeners of the elloramycin producer Streptomyces olivaceus. J. Antibiot. 39: 856-859, 1986.

Publication

Fiedler, H.-P.: Identification of new elloramycins, anthracycline-like antibiotics, in biological cultures by high-performance liquid chromatography and diode array detection. J. Chromatogr. 361: 432-436, 1986.

Publication

Fiedler, H.-P. & A. Plaga: Separation of amino acids and antibiotics by narrow-bore and normal-bore high-performance liquid chromatography with pre-column derivatization. J. Chromatogr. 386: 229-241, 1987.

Fiedler, H.-P.: Substanzidentifizierung in biologischen Proben mit HPLC und Diodenarray-Detektion. In 3. Waldbronner Themen, Vol. 1. Ed. J. Leyrer, Hewlett-Packard Part No. 0787-0250, Waldbronn, 1987.

Publication

Fiedler, H.-P.; T. Hörner & A. Wörn: Separation of polypeptide antibiotics by reversed-phase high-performance liquid chromatography. Chromatographia 24: 433-438, 1987.

Publication

Rohr, J.; S. Eick, A. Zeeck, P. Reuschenbach, H. Zähner & H.-P. Fiedler: Tetracenomycins B3 and D3, key intermediates of the elloramycin and tetracenomycin C biosynthesis. J. Antibiot. 41: 1066-1073, 1988.

Zähner, H.; H. Drautz, H.-P. Fiedler, R. Grote, W. Keller-Schierlein, W.A. König & A. Zeeck: Ways to new metabolites from actinomycetes. In Biology of Actinomycetes '88. Eds. Y. Okami et al., pp. 171-177, Japan Scientific Soc. Press, Tokyo, 1988.

Werner, R.-G.; H. Zähner, G. Jung, T. Hörner, R. Kellner & H.-P. Fiedler: Antibiotic polypeptide, process for preparing it an the use of therof. US Patentschrift Nr. 219698, Anmeldetag: 18.07.1988, 1988.

Publication

Fiedler, H.-P.; T. Hörner & H. Decker: Purification of the hydrophilic antibiotics epidermin, gallidermin and nikkomycin Z by preparative reversed-phase HPLC. Chromatographia 26: 215-220, 1988.

Fiedler, H.-P.: Nikkomycins and polyoxins. In Natural Products Isolation. Eds. G.H. Wagman & R. Cooper, pp. 153-189, Journal of Chromatography Library, Vol. 43, Elsevier, Amsterdam, 1989.

Publication

Decker, H.; C. Bormann, H.-P. Fiedler, H. Zähner, H. Heitsch & W.A. König: Isolation of new nikkomycins from Streptomyces tendae. J. Antibiot. 42: 230-235, 1989.

Publication

Heitsch, H.; W.A. König, H. Decker, C. Bormann, H.-P. Fiedler & H. Zähner: Structure of the new nikkomycins pseudo-Z and pseudo-J. J. Antibiot. 42: 711-717, 1989.

Publication

Bormann, C.; S. Mattern, H. Schrempf, H.-P. Fiedler & H. Zähner: Isolation of Streptomyces tendae mutants with an altered nikkomycin spectrum. J. Antibiot. 42: 913-918, 1989.

Fiedler, H.-P.: Off-line HPLC-Inprozesskontrollen. BTF Biotech Forum 6: 173-177, 1989.

Fiedler, H.-P.; J. Stümpfel, A. Plaga, J. Meiwes & I. Rindfleisch: HPLC-Anwendungen in der Fermentationsanalytik. In 5. Waldbronner Themen. Ed. D. Lipinski, Hewlett-Packard Part No.0689-0420GE, Bad Homburg, 1989.

Fiedler, H.-P. & J. Meiwes: HPLC-Analytik der Ferrioxamin-Produktion. PeakInfo 2/89: 1-3, 1989.

Publication

Plaga, A.; J. Stümpfel & H.-P. Fiedler: Determination of carbohydrates in fermentation processes by high-performance liquid chromatography. Appl. Microbiol. Biotechnol. 32: 45-49, 1989.

Publication

Decker, H.; F. Walz, C. Bormann, H. Zähner, H.-P. Fiedler, H. Heitsch & W.A. König: Nikkomycins Wz and Wx, new chitin synthetase inhibitors from Streptomyces tendae. J. Antibiot. 43: 43-48, 1990.

Publication

Bormann, C.; K. Aberle, H.-P. Fiedler & H. Schrempf: Genetic complementation of Streptomyces tendae deficient in nikkomycin production. Appl. Microbiol. Biotechnol. 32: 424-430, 1990.

Publication

Hörner, T.; V. Ungermann, H. Zähner, H.-P. Fiedler, R. Utz, R. Kellner & G. Jung: Comparative studies on the fermentation of lantibiotics, produced by staphylococci. Appl. Microbiol. Biotechnol. 32: 511-517, 1990.

Publication

Meiwes, J.; H.-P. Fiedler, H. Zähner, S. Konetschny-Rapp & G. Jung: Production of desferrioxamin E and new analogues by directed fermentation and feeding fermentation. Appl. Microbiol. Biotechnol. 32: 505-510, 1990.

Publication

Meiwes, J.; H.-P. Fiedler, H. Haag, H. Zähner, S. Konetschny-Rapp & G. Jung: Isolation and characterization of staphyloferrin A, a compound with siderophore activity from Staphylococcus hyicus DSM 20459. FEMS Microbiol. Lett. 67: 201-206, 1990.

Fiedler, H.-P.; J. Meiwes, I. Werner, S. Konetschny-Rapp & G. Jung: Identification of new ferrioxamines by HPLC and diode array detection. J. Chromatogr. 513: 255-262, 1990.

Huber, L. & H.-P. Fiedler: HPLC with computerized diode array detection in pharmaceutical research. In HPLC in the Pharmaceutical Industry. Eds. G.W. Fong & S.K. Lam, pp. 123-146, Marcel Dekker, New York, 1991.

Publication

Fiedler, H.-P. & J. Wachter: High-performance liquid chromatographic analysis of bleomycins. J. Chromatogr. 536: 343-347, 1991.

Publication

Ungermann, V.; T. Hörner, R. Utz, H.-P. Fiedler & H. Zähner: Comparative studies on the fermentation of lantibiotics, produced by staphylococci. In Biochemical Engineering – Stuttgart. Eds. M. Reuss et al., pp. 301-305, Gustav Fischer, Stuttgart, 1991.

Publication

Decker, H.; U. Pfefferle, C. Bormann, H. Zähner, H.-P. Fiedler, K.-H. van Pée, M. Rieck & W.A. König: Enzymatic bromation of nikkomycin Z. J. Antibiot. 44: 626-634, 1991.

Fiedler, H.-P.; H. Drautz, T. Schüz, J. Wachter & U. Hartjen: Anwendungen von HPLC, Diodenarraydetektion und Spektrenbibliothek beim Screening nach neuen Naturstoffen. In 7. Waldbronner Themen. Ed. L. Winzer, pp. 173-185, Hewlett-Packard Part.-Nr. 0791-0705GE, Bad Homburg, 1991.

Publication

Decker, H.; H. Zähner, H. Heitsch, W.A. König & H.-P. Fiedler: Structure-activity relationships of the nikkomycins. J. Gen. Microbiol. 137: 1805-1813, 1991.

Publication

Ungermann, V.; K. Goeke, H.-P. Fiedler & H. Zähner: Optimization of fermentation and purification of gallidermin and epidermin. In Nisin and Novel Lantibiotics. Eds. G. Jung & H.P. Sahl, pp. 410-421, Escom, Leiden, 1991.

Schüz, T.C.; H.-P. Fiedler, H. Zähner, M. Rieck & W.A. König: Nikkomycins Sz, Sx, Soz and Sox, new intermedates associated to the nikkomycin biosynthesis of Streptomyces tendae. J. Antibiot. 45: 199-206, 1992.

Fiedler, H.-P. & A. Kohn: HPLC screening of new bacterial drugs using UV absorbance spectral libraries. Hewlett-Packard Application Note, Publication No. 12-5091-4331E, 1992.

Thiermann, F.; G. Bongs, K.-H. van Pée, D. Braun, H.-J. Cullmann, H.-P. Fiedler & H. Zähner: In vitro- and in vivo-halogenation of natural products by bacterial peroxidases. In DECHEMA Biotechnology Conferences, Vol. 5. Eds. G. Kreysa & A.J. Driesel, pp. 17-20, VCH Verlagsgesellschaft, Weinheim, 1992.

Braun, D.; H.-J. Cullmann, H.-P. Fiedler, H. Zähner, F. Thiermann & K.-H. van Pée: Enzymatic halogenation of microbial metabolites with a non-heme bromoperoxidase from Streptomyces aureofaciens TÜ 24. In DECHEMA Biotechnology Conferences, Vol. 5. Eds. G. Kreysa & A.J. Driesel, pp. 225-230, VCH Verlagsgesellschaft, Weinheim, 1992.

Fiedler, H.-P.; A. Kulik, J. Sauerbier & T.C. Schüz: Preparative liquid chromatographic methods for separation of nucleoside-peptide antibiotics of highest purity. In DECHEMA Biotechnology Conferences, Vol. 5. Eds. G. Kreysa & A.J. Driesel, pp. 635-641, VCH Verlagsgesellschaft, Weinheim, 1992.

Tschierske, M.; K. Goeke, H.-P. Fiedler & H. Zähner: Desferrioxamine E: optimization of the production process and new hydroxamate-type siderophores obtained by precursor directed biosynthesis. In DECHEMA Biotechnology Conferences, Vol. 5. Eds. G. Kreysa & A.J. Driesel, pp. 761-764, VCH Verlagsgesellschaft, Weinheim, 1992.

Publication

Hoff, H.; H. Drautz, H.-P. Fiedler, J.E. Schultz, W. Keller-Schierlein, S. Philips, M. Ritzau & A. Zeeck: Metabolic products of microorganisms. 261. Obscurolides, a novel class of phosphodiesterase inhibitors from Streptomyces. I. Production, isolation, structural elucidation and biological activitiy of obscurolides A1 to A4. J. Antibiot. 45: 1096-1107, 1992.

Fiedler, H.-P.; T. Schüz & H. Decker: An overview of nikkomycins: history, biochemistry, and applications. In Cutaneous Antifungal Agents: Compounds in Clinical Practice and Development. Eds. J.W. Rippon & R.A. Fromtling, pp. 325-352, Marcel Dekker, New York, 1993.

Fiedler, H.-P. & A. Kohn: High performance liquid chromatographic screening of new bacterial drugs using UV absorbance spectral libraries. Europ. Microbiol. 2 (1): 39-44, 1993.

Publication

Seiffert, A.; K. Goeke, H.-P. Fiedler & H. Zähner: Production of the siderophore enterobactin: use of four different fermentation systems and identification of the compound by HPLC. Biotechnol. Bioeng. 41: 237-244, 1993.

Publication

Fiedler, H.-P.: Biosynthetic capacities of actinomycetes. 1. Screening for secondary metabolites by HPLC and UV-visible absorbance spectral libraries. Nat. Prod. Lett. 2: 119-128, 1993.

Publication

Schüz, T.C.; H.-P. Fiedler & H. Zähner: Optimized nikkomycin production by fed-batch and continuous fermentation. Appl. Microbiol. Biotechnol. 39: 433-437, 1993.

Publication

Sanglier, J.J.; E.M.H. Wellington, V. Behal, H.-P. Fiedler, R. Ellouz Ghorbel, C. Finance, M. Hacene, A. Kamoun, D. Kelly, D.K. Mercer, S. Prinzis & C. Trigo: Novel bioactive compounds from actinomycetes. Res. Microbiol. 144: 661-663, 1993.

Publication

Haag, H.; H.-P. Fiedler, J. Meiwes, H. Drechsel, G. Jung & H. Zähner: Isolation and biological characterization of staphyloferrin B, a compound with siderophore activity from staphylococci. FEMS Microbiol. Lett. 115: 125-130, 1994.

Publication

Fiedler, H.-P.; A. Kulik, T.C. Schüz, C. Volkmann & A. Zeeck: Biosynthetic capacities of actinomycetes. 2. Juglomycin Z, a new naphthoquinone antibiotic from Streptomyces tendae. J. Antibiot. 47: 1116-1122, 1994.

Zähner, H. & H.-P. Fiedler: The need for new antibiotics: possible ways forward. In Fifty Years of Antimicrobials. Eds. G.K. Darby et al., pp. 67-84, Cambridge University Press, Cambridge, 1995.

Publication

Volkmann, C.; U. Hartjen, A. Zeeck & H.-P. Fiedler: Biosynthetic capacities of actinomycetes. 3. Naphthgeranine F, a minor congener of the naphthgeranine group produced by Streptomyces violaceus. J. Antibiot. 48: 522-524, 1995.

Publication

Blum, S.; H.-P. Fiedler, I. Groth, C. Kempter, .H. Stephan, G.Nicholson, J.W. Metzger & G. Jung: Biosynthetic capacities of actinomycetes. 4. Echinoserine, a new member of the quinoxaline group, produced by Streptomyces tendae. J. Antibiot. 48: 619-625, 1995.

Kuhn, W. & H.-P. Fiedler: Sekundärmetabolismus bei Mikroorganismen. Beiträge zur Forschung. Attempto Verlag, Tübingen, 1995.

Fiedler, H.-P.: The Nikkomycin Story. In Sekundärmetabolismus bei Mikro¬organismen. Eds. W. Kuhn & H.-P. Fiedler, pp. 79-89, Attempto Verlag, Tübingen, 1995.

Pfefferle, U.; K. Ochi & H.-P. Fiedler: The stringent response and the induction of nikkomycin production in Streptomyces tendae. Actinomycetol. 9: 118-123, 1995.

Publication

Blum, S.; I. Groth, J. Rohr & H.-P. Fiedler: Biosynthetic capacities of actinomycetes. 5. Dioxolides, novel secondary metabolites from Streptomyces tendae. J. Basic Microbiol. 36: 19-25, 1996.

Publication

Burkhardt, K.; H.-P. Fiedler, S. Grabley, R. Thiericke & A. Zeeck: New cineromycins and musacins obtained by metabolite pattern analysis of Streptomyces griseoviridis (FH-S 1832). I. Taxonomy, fermentation, isolation and biological activity. J. Antibiot. 49: 432-437, 1996.

Publication

Fiedler, H.-P.; M. Nega, C. Pfefferle, I. Groth, C. Kempter, H. Stephan & J.W. Metzger: Kanchanamycins, new polyol macrolide antibiotics produced by Streptomyces olivaceus Tü 4018. I. Taxonomy, fermentation, isolation and biological activities. J. Antibiot. 49: 758-764, 1996.

Publication

Stephan, H.; C. Kempter, J.W. Metzger, G. Jung, O. Potterat, C. Pfefferle & H.-P. Fiedler: Kanchanamycins, new polyol macrolide antibiotics produced by Streptomyces olivaceus Tü 4018. II. Structure elucidation. J. Antibiot. 49: 765-769, 1996.

Publication

Pfefferle, C.; C. Kempter, J.W. Metzger & H.-P. Fiedler: (E)-4-oxonon-2-enoic acid, an antibiotically active fatty acid produced by Streptomyces olivaceus Tü 4018. J. Antibiot. 49: 826-828, 1996.

Breckel, A.; H.-P. Fiedler, H. Zähner & M. Harder: Production of gallidermin by Staphylococcus gallinarum Tü 3928. In Biochemical Engineering 3. Ed. R.D. Schmid, pp. 62-66, Kurz, Stuttgart, 1996.

Publication

Schrenk, D.; D. Riebniger, M. Till, S. Vetter & H.-P. Fiedler: Tryptanthrins: a novel class of agonists of the aryl hydrocarbon receptor. Biochem. Pharmacol. 54: 165-171, 1997.

Publication

Zwicker, N.; U. Theobald, H. Zähner & H.-P. Fiedler: Optimization of fermentation conditions for the production of ethylene-diamine-disuccinic acid by Amycolatopsis orientalis. J. Industr. Microbiol. Biotechnol. 19: 280-285, 1997.

Publication

Kempf, M.; U. Theobald & H.-P. Fiedler: Influence of dissolved O2 on the fermentative production of gallidermin by Staphylococcus gallinarum. Biotechnol. Lett. 19: 1063-1065, 1997.

Publication

Pfefferle, C.; J. Breinholt, H. Gürtler & H.-P. Fiedler: 1-Hydroxy-4-methoxy-2-naphthoic acid, a herbicidal compound produced by Streptosporangium cinnabarinum ATCC 31213. J. Antibiot. 50: 1067-1068, 1997.

Publication

Breinholt, J.; A. Kulik, H. Gürtler & H.-P. Fiedler: Tigloside: a new tigloylated tetrasaccharide from Amycolatopsis sp.. Acta Chem. Scand. 52: 1239-1242, 1998.

Publication

Kulik, A. & H.-P. Fiedler: Some aspects of the purification of anthraquinone antibiotics by preparative reversed-phase chromatography. J. Chromatogr. A 812: 117-121, 1998.

Publication

Richter, M.; J.M. Willey, R. Süssmuth, G. Jung & H.-P. Fiedler: Streptofactin, a novel biosurfactant with aerial mycelium inducing acitivity from Streptomyces tendae Tü 901/8c. FEMS Microbiol. Lett. 163: 165-171, 1998.

Publication

Höltzel, A.; C. Kempter, J.W. Metzger, G. Jung, I. Groth, T. Fritz & H.-P. Fiedler: Spirofungin, a new antifungal antibiotic from Streptomyces violaceusniger Tü 4113. J. Antibiot. 51: 699-707, 1998.

Publication

Paululat, T.; A. Zeeck, J.M. Gutterer & H.-P. Fiedler: Biosynthesis of polyketomycin produced by Streptomyces diastatochromogenes Tü 6028. J. Antibiot. 52: 96-101, 1999.

Publication

Kempf, M.; U. Theobald & H.-P. Fiedler: Economic improvement of the fermentative production of gallidermin by Staphylococcus gallinarum. Biotechnol. Lett. 21: 663-667, 1999.

Publication

Maier, A.; J. Müller, P. Schneider, H.-P. Fiedler, I. Groth, F.S.K. Tayman, F. Teltschik, C. Günther & G. Bringmann: (2E,4Z)-Decadienoic acid and (2E,4Z,7Z)-decatrienoic acid, two herbicidal metabolites from Streptomyces viridochromogenes Tü 6105. Pestic. Science 55: 733-739, 1999.

Stegmann, E.; U. Theobald, N. Zwicker, K. Wilken, H.-P. Fiedler & W. Wohlleben: S,S-EDDS (Ethylendiamindisuccinat): Ein mikrobiologisch hergestellter Komplexbildner – eine Alternative zu EDTA?. GIT Labor-Fachzeitschr. 43: 1044-1046, 1999.

Publication

Kempf, M.; U. Theobald & H.-P. Fiedler: Correlation between the consumption of amino acids and the production of the antibiotic gallidermin by Staphylococcus gallinarum. Biotechnol. Lett. 21: 959-963, 1999.

Publication

Kempf, M.; U. Theobald & H.-P. Fiedler: Production of the antibiotic gallidermin by Staphylococcus gallinarum - development of a scale-up procedure. Biotechnol. Lett. 22: 123-128, 2000.

Publication

Pfefferle, C.; J. Breinholt, C.E. Olsen, R.M. Kroppenstedt, E.M.H. Wellington, H. Gürtler & H.-P. Fiedler: Kyanomycin, a complex of unusual anthracycline-phospholipid hybrids from Nonomuria species. J. Nat. Prod. 63: 295-298, 2000.

Publication

Pfefferle, C.; U. Theobald, G. Gürtler & H.-P. Fiedler: Improved secondary metabolite production in the genus Streptosporangium by fermentation. J. Biotechnol. 80: 135-142, 2000.

Publication

Ferguson, A.D.; V. Braun, H.-P. Fiedler, J.W. Coulton, K. Diederichs & W. Welte: Crystal structure of the antibiotic albomycin in complex with the outer membrane transporter FhuA. Protein Science 9: 956-963, 2000.

Publication

Schimana, J.; H.-P. Fiedler, I. Groth, R. Süssmuth, W. Beil, M. Walker & A. Zeeck: Simocyclinones, novel cytostatic angucyclinone antibiotics produced by Streptomyces antibioticus Tü 6040. I. Taxonomy, fermentation, isolation and biological activities. J. Antibiot. 53: 779-787, 2000.

Publication

Kempf, M.; U. Theobald & H.-P. Fiedler: The antibiotic gallidermin – evolution of a production process. In Novel Frontiers in the Production of Compounds for Biomedical Use, Vol. 1A. Eds. A. van Broekhoven et al., pp. 35-55, Kluwer Academic Press, Dordre, 2001.

Publication

Fiedler, H.-P.; P. Krastel, J. Müller, K. Gebhardt & A. Zeeck: Enterobactin: the characteristic catecholate siderophore of Enterobacteriaceae is produced by Streptomyces species. FEMS Microbiol. Lett. 196: 147-151, 2001.

Publication

Theobald, U.; J. Schimana & H.-P. Fiedler: Microbial growth and production kinetics of Streptomyces antibioticus Tü 6040. Antonie van Leeuwenhoek 78: 307-313, 2000.

Publication

Gebhardt, K.; R. Pukall & H.-P. Fiedler: Streptocidins A-D, novel cyclic decapeptide antibiotics produced by Streptomyces sp. Tü 6071. I. Taxonomy, fermentation, isolation and biological properties. J. Antibiot. 54: 428-433, 2001.

Publication

Höltzel, A.; R.D. Süssmuth, R.W. Jack, G.J. Nicholson, K. Gebhardt, H.-P. Fiedler & G. Jung: Streptocidins A-D, novel cyclic decapeptide antibiotics produced by Streptomyces sp. Tü 6071. II. Structure elucidation.. J. Antibiot. 54: 434-440, 2001.

Publication

Bertasso, M.; M. Holzenkämpfer, A. Zeeck, F. Dall‘Antonia & H.-P. Fiedler: Bagremycin A and B, novel antibiotics from Streptomyces sp. Tü 4128. J. Antibiot. 54: 730-736, 2001.

Publication

Tünnemann, R.; M. Mehlmann, R. Süssmuth, B. Bühler, S. Pelzer, W. Wohlleben, H.-P. Fiedler, K.-H. Wiesmüller, G. Gauglitz & G. Jung: Optical biosensors. Monitoring studies of glycopeptide antibiotic fermentation using white light interference. Anal. Chem. 73: 4313-4318, 2001.

Publication

Schimana, J.; M. Walker, A. Zeeck & H.-P. Fiedler: Simocyclinones: diversity of metabolites is dependent on fermentation conditions. J. Ind. Microbiol. Biotechnol. 27: 144-148, 2001.

Publication

Fiedler, H.-P. & H. Zähner: Screening for new secondary metabolites from micro¬organisms. In Microbial Fundamentals of Biotechnology. Eds., V. Braun & F. Götz, pp.16-51, Wiley-VCH, Weinheim, 2001.

Publication

Holzenkämpfer, M.; M. Walker, A. Zeeck, J. Schimana & H.-P. Fiedler: Simocyclinones, novel cytostatic angucyclinone antibiotics produced by Streptomyces antibioticus Tü 6040. II. Structure elucidation and biosynthesis. J. Antibiot. 55: 301-307, 2002.

Publication

Trefzer, A.; S. Pelzer, J. Schimana, S. Stockert, C. Bihlmaier, H.-P. Fiedler, K. Welzel, A. Vente & A. Bechthold: Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic. Antimicrob. Agents Chemother. 46: 1174-1182, 2002.

Publication

Schimana, J.; K. Gebhardt, J. Müller, A. Höltzel, D.G. Schmid, R. Süssmuth, R. Pukall & H.-P. Fiedler: Arylomycins A and B, new biaryl-bridged lipopeptide antibiotics produced by Streptomyces sp. Tü 6075. I. Taxonomy, fermentation, isolation and biological activities. J. Antibiot. 55: 565-570, 2002.

Publication

Höltzel, A.; D.G. Schmid, G.J. Nicholson, S. Stevanovic, J. Schimana, K. Gebhardt, H.-P. Fiedler & G. Jung: Arylomycins A and B, new biaryl-bridged lipopeptide antibiotics produced by Streptomyces sp. Tü 6075. II. Structure elucidation. J. Antibiot. 55: 571-577, 2002.

Publication

Galm, U.; J. Schimana, H.-P. Fiedler, J. Schmidt, S.-M. Li & L. Heide: Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tü 6040. Arch. Microbiol. 178: 102-114, 2002.

Publication

Gebhardt, K.; J. Schimana, P. Krastel, K. Dettner, J. Rheinheimer, A. Zeeck & H.-P. Fiedler: Endophenazines A-D, new phenazine antibiotics from the arthropod associated endosymbiont Streptomyces anulatus. I. Taxonomy, fermentation, isolation and biological properties. J. Antibiot. 55: 794-800, 2002.

Publication

Krastel, P.; A. Zeeck, K. Gebhardt, H.-P. Fiedler & J. Rheinheimer: Endophenazines A-D, new phenazine antibiotics from the arthropod associated endosymbiont Streptomyces anulatus. II. Structure elucidation. J. Antibiot. 55: 801-806, 2002.

Publication

Muschko, K.; G. Kienzlen, H.-P. Fiedler, W. Wohlleben & D. Schwartz: Tricarboxylic acid cycle aconitase activity during the life cycle of Streptomyces viridochromogenes Tü494. Arch. Microbiol. 178: 499-505, 2002.

Publication

Gebhardt, K.; J. Schimana, J. Müller, H.-P. Fiedler, H.G. Kallenborn, M. Holzenkämpfer, P. Krastel, A. Zeeck, J. Vater, A. Höltzel, J. Rheinheimer & K. Dettner: Screening for biologically active metabolites with endosymbiotic bacilli isolated from arthropods. FEMS Microbiol. Lett. 217: 199-205, 2002.

Publication

Bertasso, M.; M. Holzenkämpfer, A. Zeeck, E. Stackebrandt, W. Beil & H.-P. Fiedler: Ripromycin and other polycyclic macrolactams from Streptomyces sp. Tü 6239: taxonomy, fermentation, isolation and biological properties. J. Antibiot. 56: 364-371, 2003.

Publication

Dieter, A.; A. Hamm, H.-P. Fiedler, M. Goodfellow, W.E.G. Müller, R. Brun, W. Beil & G. Bringmann: Pyrocoll, an antibiotic, antiparasitic and antitumor compound produced by a novel alkaliphilic Streptomyces strain. J. Antibiot. 56: 639-646, 2003.

Publication

Fiedler, H.-P.; R.D. Süssmuth, H. Zähner & A.T. Bull: Polyzyklische Makrolactone. P 43 326 DE, October 1, 2003.

Publication

Höltzel, A.; A. Dieter, D.G. Schmid, R. Brown, M. Goodfellow, W. Beil, G. Jung & H.-P. Fiedler: Lactonamycin Z, an antibiotic and antitumor compound produced by Streptomyces sanglieri strain AK 623. J. Antibiot. 56: 1058-1061, 2003.

Publication

Fiedler, H.-P.: Screening for bioactivity. In Microbial Diversity and Bioprospecting. Ed., A.T. Bull, pp. 324-335, ASM Press, Washington, 2004.

Publication

Riedlinger, J.; A. Reicke, H. Zähner, B. Krismer, A.T. Bull, L.A. Maldonado, A.C. Ward, M. Goodfellow, B. Bister, D. Bischoff, R. Süssmuth & H.-P. Fiedler: Abyssomicins, inhibitors of the para-aminobenzoic acid pathway produced by the marine Verrucosispora strain AB-18-032. J. Antibiot. 57: 271-279, 2004.

Publication

Bister, B.; D. Bischoff, M. Ströbele, J. Riedlinger, A. Reicke, F. Wolter, A.T. Bull, H. Zähner, H.-P. Fiedler & R.D.Süssmuth: Abyssomicin C – a polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway. Angew. Chem. Int. Ed. 43: 2574-2576, 2004.

Publication

Maier, A.; J. Riedlinger, H.-P. Fiedler & R. Hampp: Actinomycetales bacteria from a spruce stand: characterization and effects on growth of root symbiotic, and plant parasitic soil fungi in dual culture. Mycol. Progr. 3: 129-136, 2004.

Publication

Fiedler, H.-P. & M. Goodfellow: Alkaliphilic streptomycetes as a source of novel secondary metabolites. Microbiol. Australia 25 (2): 27-29, 2004.

Publication

Gebhardt, K.; J. Schimana, A. Höltzel, K. Dettner, S. Draeger, W. Beil, J. Rheinheimer & H.-P. Fiedler: Aspochalamins A-D and aspochalasin Z produced by the endosymbiotic fungus Aspergillus niveus LU 9575. I. Taxonomy, fermentation, isolation and biological activities. J. Antibiot. 57: 707-714, 2004.

Publication

Höltzel, A.; D.G. Schmid, G.J. Nicholson, P. Krastel, A. Zeeck, K. Gebhardt, H.-P. Fiedler & G. Jung: Aspochalamins A-D and aspochalasin Z produced by the endosymbiotic fungus Aspergillus niveus LU 9575. II. Structure elucidation. J. Antibiot. 57: 715-720, 2004.

Bertasso, M.; M. Holzenkämpfer, A. Zeeck, W. Beil & H.-P. Fiedler: Bagremycins are new para-coumaric acid derived antibiotics produced by Streptomyces sp. Tü 4128. In Biotechnological Advances and Applications in Bioconversion of Renewable Raw Materials. Eds., R. Jonas et al., pp.86-91, Döringdruck, Braunschweig, 2004.

Publication

Antal, N.; H.-P. Fiedler, E. Stackebrandt, W. Beil, K. Ströch & A. Zeeck: Retymicin, galtamycin B, saquayamycin Z and ribofuranosyllumichrome, novel secondary metabolites from Micromonospora sp. Tü 6368. I. Taxonomy, fermentation, isolation and biological properties. J. Antibiot. 58: 95-102, 2005.

Publication

Ströch, K.; A. Zeeck, N. Antal & H.-P. Fiedler: Retymicin, galtamycin B, saquayamycin Z and ribofuranosyllumichrome, novel secondary metabolites from Micromonospora sp. Tü 6368. II. Structure elucidation. J. Antibiot. 58: 103-110, 2005.

Publication

Fiedler, H.-P.; C. Bruntner, A.T. Bull, A.C. Ward, M. Goodfellow, O. Potterat, C. Puder & G. Mihm: Marine actinomycetes as a source of novel secondary metabolites. Antonie van Leeuwenhoek 87: 37-42, 2005.

Publication

Flatman, R.H.; A.J. Howells, L. Heide, H.-P. Fiedler & A. Maxwell: Simocyclinone D8: an inhibitor of DNA gyrase with a novel mode of action. Antimicrob. Agents Chemother. 49: 1093-1100, 2005.

Publication

Bruntner, C.; T. Binder, W. Pathom-aree, M. Goodfellow, A.T. Bull, O. Potterat, C. Puder, S. Hörer, A. Schmid, W. Bolek, K. Wagner, G. Mihm & H.-P. Fiedler: Frigocyclinone, a novel angucyclinone antibiotic produced by a Streptomyces strain from Antarctica. J. Antibiot. 58: 346-349, 2005.

Publication

Bringmann, G.; G. Lang, K. Maksimenka, A. Hamm, T.A.M. Gulder, A. Dieter, A.T. Bull, J.E.M. Stach, N. Kocher, W.E.G. Müller & H.-P. Fiedler: Gephyromycin, the first bridged angucyclinone, from Streptomyces griseus strain NTK 14. Phytochemistry 66: 1365-1372, 2005.

Publication

Riedlinger, J.; S.D. Schrey, M.T. Tarkka, R. Hampp, M. Kapur & H.-P. Fiedler: Auxofuran, a novel metabolite that stimulates the growth of fly agaric, is produced by the mycorrhiza helper bacterium Streptomyces AcH 505. Appl. Environ. Microbiol. 72: 3550-3557, 2006.

Publication

Radzom, M.; A. Zeeck, N. Antal & H.-P. Fiedler: Fogacin, a novel cyclic octaketide produced by Streptomyces strain Tü 6319. J. Antibiot. 59: 315-317, 2006.

Publication

Baur, S.; J. Niehaus, A.D. Karagouni, E.A. Katsifas, K. Chalkou, C. Meintanis, A. Jones, M. Goodfellow, A.C. Ward, W. Beil, K. Schneider, R.D. Süssmuth & H.-P. Fiedler: Fluostatins C~E novel members of the fluostatin family produced by Streptomyces strain Acta 1383. J. Antibiot. 59: 293-297, 2006.

Publication

Bringmann, G.; T.F. Noll, T.A.M. Gulder, M. Grüne, M. Dreyer, C. Wilde, F. Pankewitz, M. Hilker, G.D. Payne, A.L. Jones, M. Goodfellow & H.-P. Fiedler: Different polyketide folding modes converge to an identical molecular architecture. Nature Chem. Biol. 2: 429-433, 2006.

Publication

Graf, E.; K. Schneider, G. Nicholson, M. Ströbele, A.L. Jones, M. Goodfellow, W. Beil, R.D. Süssmuth & H.-P. Fiedler: Elloxazinones A and B, new aminophenoxazinones from Streptomyces griseus Acta 2871. J. Antibiot. 60: 277-284, 2007.

Publication

Schneider, K.; I. Rose, S. Vikineswary, A.L. Jones, M. Goodfellow, G. Nicholson, W. Beil, R. Süssmuth & H.-P. Fiedler: Nocardichelins A and B, siderophores from Nocardia strain Acta 3026. J. Nat. Prod. 70: 932-935, 2007.

Publication

Keller, S.; G. Nicholson, C. Drahl, E. Sorensen, H.-P. Fiedler & R.D. Süssmuth: Abyssomicins G and H and atrop-abyssomicin C from the marine Verrucosispora strain AB-18-032. J. Antibiot. 60: 391-394, 2007.

Publication

Textor, A.; I. Papastavrou, J. Siewert, J. Magull, A. Kulik, H.-P. Fiedler, P. von Zezschwitz & S. Grond: Spridionic acid, a novel metabolite from Streptomyces sp., part 1: structure elucidation and Diels-Alder-type biosynthesis. Chem. Eur. J. 13: 7416-7423, 2007.

Publication

Zhang, X.; L.B. Alemany, H.-P. Fiedler, M. Goodfellow & R.P. Parry: Biosynthetic investigations of lactonamycin and lactonamycin Z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit. Antimicrob. Agents Chemother. 52: 574-585, 2008.

Publication

Fiedler, H.-P.; C. Bruntner, J. Riedlinger, A.T. Bull, G. Knutsen, A.L. Jones, M. Goodfellow, W. Beil, K. Schneider, S. Keller & R.D. Süssmuth: Proximicins A~C, novel aminofuran antibiotics from marine Verrucosispora strains. J. Antibiot. 61: 158-163, 2008.

Publication

Schneider, K.; S. Keller, F.E. Wolter, L. Röglin, W. Beil, O. Seitz, G. Nicholson, C. Bruntner, J. Riedlinger, H.-P. Fiedler & R.D. Süssmuth: Proximicins A, B and C – antitumor furan analogues of netropsin from the marine actinomycete Verrucosispora induce upregulation of p53 and the cyclin kinase inhibitor p21. Angew. Chem. Int. Ed. 47: 3258-3261, 2008.

Publication

Huang, X.; J. He, X. Niu, K.-D. Menzel, H.-M. Dahse, S. Grabley, H.-P. Fiedler, I. Sattler & C. Hertweck: Benzopyrenomycin, a cytotoxic bacterial polyketide metabolite with an unprecedented benzo[a]pyrene-type carbacyclic ring system. Angew. Chem. Int. Ed. 47: 3995-3998, 2008.

Publication

Schneider, K.; E. Graf, E. Irran, G. Nicholson, F.M. Stainsby, M. Goodfellow, S.A. Borden, S. Keller, R.D. Süssmuth & H.-P. Fiedler: Bendigoles A~C, new steroids from Gordonia australis Acta 2299. J. Antibiot. 61: 356-364, 2008.

Publication

Paululat, T.; E.A. Katsifas, A.D. Karagouni & H.-P. Fiedler: Grecoketides A and B, new naphthoquinones from Streptomyces sp. Acta 1362. Eur. J. Org. Chem. 2008: 5283-5288, 2008.

Publication

Fiedler, H.-P.; A. Dieter, T.A.M. Gulder, I. Kajahn, A. Hamm, M. R. Brown, A.L. Jones, Goodfellow, W.E.G. Müller & G. Bringmann: Genoketides A1 and A2, new octaketides and biosynthetic intermediates of chrysophanol produced by Streptomyces sp. AK 671. J. Antibiot. 61: 464-473, 2008.

Publication

Sommer, P.S.M.; R.C. Almeida, W. Beil, R.D. Süßmuth & H.-P. Fiedler: Nataxazole, a new benzoxazole derivative with antitumor activity produced by Streptomyces sp. Tü 6176. J. Antibiot. 61: 683-686, 2008.

Publication

Hohmann, C.; K. Schneider, C. Bruntner, R. Brown, A.L. Jones, M. Goodfellow, M. Krämer, J.F. Imhoff, G. Nicholson, H.-P. Fiedler & R.D. Süssmuth: Albidopyrone, a new alpha-pyrone containing metabolite from marine-derived Streptomyces sp. NTK 227. J. Antibiot. 62: 75-79, 2009.

Publication

Hohmann, C.; K. Schneider, C. Bruntner, E. Irran, G. Nicholson, A.T. Bull, A.L. Jones, R. Brown, J.E.M. Stach, M. Goodfellow, W. Beil, J.F. Imhoff, R.D. Süssmuth & H.-P. Fiedler: Caboxamycin, a new antibiotic of the benzoxazole family from deep-sea strain Streptomyces sp. NTK 937. J. Antibiot. 62: 99-104, 2009.

Publication

Oppegard, L.M.; B.L. Hamann, K.R. Streck, K.C. Ellis, H.-P. Fiedler, A.B. Khodursky & H. Hiasa: In vivo and in vitro patterns of the activity of simocyclinone D8, an angucyclinone antibiotic from Streptomyces antibioticus. Antimicrob. Agents Chemother. 53: 2110-2119, 2009.

Publication

Saleh, O.; B. Gust, B. Boll, H.-P. Fiedler & L. Heide: Aromatic prenylation in the phenazine biosynthesis: dihydrophenazine-1-carboxylate dimethylallyltransferase from Streptomyces anulatus. J. Biol. Chem. 284: 14439-14447, 2009.

Publication

Schulz, D.; J. Nachtigall, J. Riedlinger, K. Schneider, K. Poralla, J.F. Imhoff, W. Beil, G. Nicholson, H.-P. Fiedler & R.D. Süssmuth: Piceamycin and its N-acetylcysteine adduct is produced by Streptomyces sp. GB 4-2. J. Antibiot. 62: 513-518, 2009.

Publication

Helaly, S.; K. Schneider, J. Nachtigall, S. Vikineswary, G.Y.A. Tan, H. Zinecker, J.F. Imhoff, R.D. Süssmuth & H.-P. Fiedler: Gombapyrones, new alpha-pyrone metabolites produced by Streptomyces griseoruber Acta 3662. J. Antibiot. 62: 445-452, 2009.

Publication

Laiple, K.J.; T. Härtner, H.-P. Fiedler, W. Wohlleben & T. Weber: The kirromycin gene cluster of Streptomyces collinus Tü 365 codes for an aspartate-alpha-decarboxylase, KirD, which is involved in the biosynthesis of the precursor beta-alanine. J. Antibiot. 62: 465-468, 2009.

Publication

Le, T.B.K.; H.-P. Fiedler, C.D. den Hengst, S.K. Ahn, A. Maxwell & M.J. Buttner: Coupling of the biosynthesis and export of the DNA gyrase inhibitor simocyclinone in Streptomyces antibioticus. Molec. Microbiol. 72: 1462-1474, 2009.

Publication

Schneider, K.; J. Nachtigall, A. Hänchen, G. Nicholson, M. Goodfellow, R.D. Süssmuth & H.-P. Fiedler: Lipocarbazoles, new secondary metabolites from Tsukamurella pseudospumae Acta 1857 with antioxidative activity. J. Nat. Prod. 72: 1768-1772, 2009.

Publication

Bringmann, G.; T.A.M. Gulder, A. Hamm, M. Goodfellow & H.-P. Fiedler: Multiple convergence in polyketide biosynthesis: a third folding mode to the anthraquinone chrysophanol. Chem Commun. 2009: 6810-6812, 2009.

Publication

Bringmann, G.; A. Irmer, D. Feineis, T.A.M. Gulder & H.-P. Fiedler: Convergence in the biosynthesis of polyketide natural products from plants, fungi and bacteria. Phytochemistry 70: 1776-1786, 2009.

Publication

Edwards, M.J.; R.H. Flatman, L.A. Mitchenall, C.E.M. Stevenson, T.B.K. Le, T.A. Clarke, A.R. McKay, H.-P. Fiedler, M.J. Buttner, D.M. Lawson & A. Maxwell: A crystal structure of the bifunctional antibiotic, simocyclinone D8, bound to DNA gyrase. Science 326: 1415-1417, 2009.

Publication

Paululat, T.; A. Kulik, H. Hausmann, A.D. Karagouni, H. Zinecker, J.F. Imhoff & H.-P. Fiedler: Grecocyclines: new angucyclines from Streptomyces sp. Acta 1362. Eur. J. Org. Chem. 2010: 2344-2350, 2010.

Publication

Abdel-Mageed, W.M.; B.F. Milne, M. Wagner, M. Schumacher, P. Sandor, W. Pathom-aree, M. Goodfellow, A.T. Bull, K. Horikoshi, R. Ebel, M. Diedrich, H.-P. Fiedler & M. Jaspars: Dermacozines, a new phenazine family from deep-sea dermacocci isolated from a Mariana Trench sediment. Org. Biomol. Chem. 8: 2352-2362, 2010.

Publication

Nachtigall, J.; D. Schulz, W. Beil, R.D. Süssmuth & H.-P. Fiedler: Aranciamycin anhydride, a new anthracycline-type antibiotic isolated from Streptomyces sp. Tü 6384. J. Antibiot. 63: 397-399, 2010.

Publication

Nachtigall, J.; K. Schneider, G. Nicholson, M. Goodfellow, H. Zinecker, J.F. Imhoff, R.D.Süssmuth & H.-P. Fiedler: Two new aurachins from Rhodococcus sp. Acta 2257. J. Antibiot. 63: 567-569, 2010.

Publication

Goodfellow, M. & H.-P. Fiedler: A guide to successful bioprospecting: informed by actinobacterial systematics. Antonie van Leeuwenhoek 98: 119-142, 2010.

Publication

Gebhardt, K.; S.W. Meyer, J. Schinko, G. Bringmann, A. Zeeck & H.-P. Fiedler: Phenalinolactones A-D, terpenoglycoside antibiotics from Streptomyces sp. Tü 6071. J. Antibiot. 64, 229-232, 2011.

Publication

Brötz, E.; A. Kulik, S. Vikineswary, C.-T. Lim, G.Y.A. Tan, H. Zinecker, J.F. Imhoff, T. Paululat & H.-P. Fiedler: Phenelfamycins G and H, new elfamycin-type antibiotics produced by Streptomyces albospinus Acta 3619. J. Antibiot. 64, 257-266, 2011.

Publication

Pohle, S.; C. Appelt, M. Roux, H.-P. Fiedler & R.D. Süssmuth: Biosynthetic gene cluster of the non-ribosomally synthesized cyclodepsipeptide skyllamycin: deciphering unprecedented ways of unusual hydroxylation reactions. J. Am. Chem. Soc. 133: 6194-6205, 2011.

Publication

Nachtigall, J.; K. Schneider, C. Bruntner, A.T. Bull, M. Goodfellow, H. Zinecker, J.F. Imhoff, G. Nicholson, E. Irran, R.D. Süssmuth & H.-P. Fiedler: Benzoxacystol, a benzoxazine-type enzyme inhibitor from the deep-sea strain Streptomyces sp. NTK 935. J. Antibiot. 64: 453-457, 2011.

Publication

Helaly, S.E.; A. Pesic, H.-P. Fiedler & R.D. Süssmuth: Elaiomycins B and C: alkylhydrazide antibiotics from Streptomyces sp. BK 190. Org. Lett. 13: 1052-1054, 2011.

Publication

Le, T.B.K.; C.E.M. Stevenson, H.-P. Fiedler, A. Maxwell, D.M. Lawson & M.J. Buttner: Structures of the TetR-like simocyclinone efflux pump repressor, SimR, and the mechanism of ligand-mediated derepression. J. Molec. Biol. 408: 40-56, 2011.

Publication

Gottardi, E.M.; J.M. Krawczyk, H. von Suchodoletz, S. Schadt, A. Mühlenweg, G.C. Uguru, S. Pelzer, H.-P. Fiedler, M.J. Bibb, J.E.M. Stach & R.D. Süssmuth: Abyssomicin biosynthesis: formation of an unusual polyketide, antibiotic-feeding studies and genetic analysis. ChemBioChem 12: 1401-1410, 2011.

Publication

Kim, B.-Y.; S. Willbold, A. Kulik, S.E. Helaly, H. Zinecker, J. Wiese, J.F. Imhoff, M. Goodfellow, R.D. Süssmuth & H.-P. Fiedler: Elaiomycins B and C, novel alkylhydrazides produced by Streptomyces sp. BK 190. J. Antibiot. 64: 595-597, 2011.

Publication

Kim, B.-Y.; T.D. Zucci, H.-P. Fiedler & M. Goodfellow: Streptomyces cocklensis sp. nov., a novel actinomycete which produces dioxamycin. Int. J. Syst. Evol. Microbiol. 62: 279-283, 2011.

Publication

Nachtigall, J.; A. Kulik, S. Helaly, A.T. Bull, M. Goodfellow, J.A. Asenjo, A. Maier, J. Wiese, J.F. Imhoff, R.D. Süssmuth & H.-P. Fiedler: Atacamycins A-C, 22-membered antitumor macrolactones produced by Streptomyces sp. C38. J. Antibiot. 64: 775-780, 2012.

Helaly, S.; A. Kulik, H. Zinecker, K. Ramachandaran, G.Y.A. Tan, J.F. Imhoff, R.D. Süssmuth, H.-P. Fiedler and V. Sabaratnam: Langkolide, a 32-membered macrolactone antibiotic produced by Streptomyces sp. Acta 3062. J. Nat. Prod. 75: 1018-1024, 2012.

Saleh, O.; K. Flinspach, L. Westrich, A. Kulik, B. Gust, H.-P. Fiedler & L. Heide: Mutational analysis of a phenazine biosynthetic gene cluster in Streptomyces anulatus 9663. Beilstein J. Org. Chem. 8: 501-513, 2012.

Saleh, O.; T. Bonitz, K. Flinspach, A. Kulik, N. Burkhard, A. Mühlenweg, A. Vente, S. Polnick, M. Lämmerhofer, B. Gust, H.-P. Fiedler & L. Heide: Activation of a silent phenazine biosynthetic gene cluster reveals a novel natural product and a new resistance mechanism against phenazines. Med. Chem. Commun. 3: 1009-1019, 2012.

Kim, B.-Y.; T.D. Zucchi, H.-P. Fiedler & M. Goodfellow: Streptomyces staurosporinus sp. nov., a staurosporine-producing actinomycete. Int. J. Syst. Evol. Microbiol. 62: 966-970, 2012.

Schulz, D.; J. Nachtigall, U. Geisen, H. Kalthoff, J.F. Imhoff, H.-P. Fiedler & R.D. Süssmuth: Silvalactam, a 24-membered macrolactam antibiotic produced by Streptomyces sp. Tü 6392. J. Antibiot. 65:369-372, 2012.

Publication

Schrey, S.D.; E. Erkenbrack, E. Früh, S. Fengler, K. Hommel, N. Horlacher, D. Schulz, M. Ecke, A. Kulik, H.-P. Fiedler, R. Hampp & M.T. Tarkka: Production of fungal and bacterial growth modulating metabolites is widespread among mycorrhiza-associated streptomycetes.. BMC Microbiol. 12:164, 2012.

Goodfellow, M.; J.E.M. Stach, R. Brown, A.N.V. Bonda, A.L. Jones, J. Mexson, H.-P. Fiedler, T.D. Zucchi & A.T. Bull.: Verrucosispora maris sp. nov., a novel deep-sea actinomycete isolated from a marine sediment which produces abyssomicins. Antonie van Leeuwenhoeck 101, 185-193, 2012.

Manderscheid, Niko; S.E. Helaly, A. Kulik, J. Wiese, J.F. Imhoff, H.-P. Fiedler & R.D. Süssmuth: Elaiomycins K and L, new azoxy antibiotics from Streptomyces sp. Tü 6399 . J. Antibiot. 66: 85-88, 2013.

Horlacher, N.; J. Nachtigall, D. Schulz, R.D. Süssmuth, R. Hampp, H.-P. Fiedler & S.D. Schrey: Biotransformation of the fungal phytotoxin fomannoxin by soil streptomycetes. J. Chem. Ecol. 39: 931-941, 2013.

Kalyon, B.; G.-Y.A. Tan, J.M. Pinto, C.-Y. Foo, J. Wiese, J.F. Imhoff, R.D. Süssmuth, V. Sabaratnam & H.-P. Fiedler: Langkocyclines: novel angucycline antibiotics from Streptomyces sp. Acta 3034. J. Antibiot. 66: 609-616, 2013.

Helaly, S.E.; M. Goodfellow, H. Zinnecker, J.F. Imhoff, R.D. Süssmuth & H.-P. Fiedler: Warkmycin, a novel angucycline antibiotic produced by Streptomyces sp. Acta 2930. J. Antibiot. 66: 669-674, 2013.

Jetter, P.; C. Steinert, M. Knauer, G. Zhang, T. Bruhn, J. Wiese, J.F. Imhoff, H.-P. Fiedler & G. Bringmann: New bhimamycins from Streptomyces sp. AK 671. J. Antibiot. 66: 719-726, 2013.

Publication

Dalmas, F.R.; L. Astarita, L. DeFilippis, E. Magel, H.-P. Fiedler, R. Bauer & R. Hampp: Growth inhibition of an Araucaria angustifolia (Coniferopsida) fungal seed pathogen, Neofusicoccum parvum, by soil streptomycetes. BMC Microbiol. 13:168, 2013.

Wagner, M.; W.M. Abdel-Mageed, R. Ebel, A.T. Bull, M. Goodfellow, H.-P. Fiedler & M. Jaspars: Dermacozines H-J isolated from a deep-sea strain Dermacoccus abyssi from Mariana Trench sediments. J. Nat. Prod. 77: 416-420, 2014.

Schubert, V.; F. Di Meo, P.-L. Saaidi, S. Bartoschek, H.-P. Fiedler, P. Trouillas & R.D. Süssmuth: Stereochemistry and conformation of skyllamycin, a non-ribosomally synthesized peptide from Streptomyces sp. Acta 2897. Chemistry 20: 4948-4955, 2014.

Bertazzo, M.; M.C. Montero-Calasanz, M. Martinez-Garcia, C. Spröer, P. Schumann, R.M. Kroppenstedt, E. Stackebrandt, H.-P. Klenk & H.-P. Fiedler: Geodermatophilus brasiliensis sp. nov., isolated from Brazilian soil. J. Syst. Evol. Microbiol. 64: 2841-2848, 2014.

Olano, C; C. Cano-Prieto, A.A. Losada, A.T. Bull, M. Goodfellow, H.-P. Fiedler, C. Méndez & J.A. Salas: Draft genome sequence of marine actinomycete Streptomyces sp. strain NTK 937, producer of the benzoxazole antibiotic caboxamycin. Genome Announcements 01/2014 2 (4), 2014.

Fiedler, H.-P.: Suche nach neuen Wirkstoffproduzenten: Isolierung und taxonomische Charakterisierung von Actinomyceten - ein "Muss" für ein erfolgreiches Wirkstoffscreening. labor&more 10.14: 30-35, 2014.

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